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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Naringenin, Temozolomide
Phytochemical Name Naringenin (PubChem CID: 439246 )
Anticancer drug Name Temozolomide (PubChem CID: 5394 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 451
Pair Name Naringenin, Temozolomide
Disease Info [ICD-11: 2A00] Glioblastoma multiforme Investigative
Biological Phenomena Inhibition-->Cell migration
In Vitro Model U-87MG ATCC Glioblastoma Homo sapiens (Human) CVCL_0022
LN-229 Glioblastoma Homo sapiens (Human) CVCL_0393
Result The study showed a marked reduction in the migration of the cells and the formation of a single cell colony.
03. Reference
No. Title Href
1 Combinatorial Effect of Temozolomide and Naringenin in Human Glioblastoma Multiforme Cell Lines. Nutr Cancer. 2022;74(3):1071-1078. doi: 10.1080/01635581.2021.1952438. Click
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